Lille and Real Madrid player each other for the first time on matchday two of the 2024/25 UEFA Champions League league phase.
A full house at the Stade Pierre Mauroy will be hoping Lille can bounce back from their opening 2-0 loss at Sporting Lisbon, but Real, unbeaten in a 90-minute match in over a year, look like they mean business once more.
Real Madrid & Over 2.5 Goals - 13/10
Kylian Mbappe has been passed fit to travel back to France after missing Sunday's Madrid derby, but even if the former PSG ace doesn't take to the pitch, Real should still have too much for Lille.
The UEFA Champions League holders arrive at the Stade Pierre Mauroy having not tasted defeat this season, nor in any of their last 36 matches.
The Spanish giants haven't lost a 90-minute match in over 12 months and will be full of confidence in Lille.
Real, who beat Stuttgart 3-1 in their opening league phase match, are 4/7 to win in Northern France, with Bruno Genesio's home side, back in the UEFA Champions League after a two-year absence, available at 9/2.
Having lost their opener 2-0 at Sporting Lisbon the French side could do without losing ground in the race for the top 24 places and at the very least the chance of progressing to the knockout stage.
And it doesn't get any easier for Lille, whose next two games are away at Atletico Madrid and at home to Juventus.
This looks a tough ask for Lille, currently fifth in Ligue 1 after a mixed start to the campaign which has featured three wins, two defeats and a draw.
At the weekend they produced their most complete performance of the campaign with a 3-0 win at Le Havre.
Lille struggled to see off both Fenerbahce and Slavia Prague in UEFA Champions League qualifying, pipping each opponent 3-2 on aggregate.
In Lisbon against Sporting they were seriously second best, conceding 18 shots while chalking up just three of their own, though Angel Gomes' 40th-minute red card didn't help their cause.
Lille need to be well organised, but the firepower Real possess through Rodrygo and Vinicius Jr is frightening - even if Mbappe sits this out.
Look at the Result/Total Goals market and back Real win & Over 2.5 at 13/10.
Benjamin Andre to be booked - 9/4
Lille club captain Benjamin Andre is on a yellow card streak which is set to continue against Real.
The tough-tackling midfielder has been booked in each of his last four games, in the 2-0 defeat at Sporting Lisbon in the UEFA Champions League as well as his last three Ligue 1 outings.
Three yellows inside 10 matches earn a suspension in France which means he misses Lille's trip to Monaco after the international break.
But it also appears to mean his juices are flowing just in time to take his frustrations out on Real's all-star tormentors.
Andre was booked 11 times last season, five short of his personal-best tally of 16 in 2021/22, so it would surprise no one if he didn't have his name taken by Italian referee Maurizio Mariani.
Time of First Corner - No Corner Before 8:00 - 5/6
Something has to give in the corners stakes with Lille amazingly conceding just 11 in six Ligue 1 matches this season, while Real have piled up 49 in eight La Liga contests.
Real also amassed 10 in their 3-1 win against Stuttgart at the Bernabeu.
Lille, despite playing away at Sporting and with 10 men for the entire second half, only gave up three corners to the Portuguese giants.
Real should dominate possession and ought to win the game but don't expect a barrage of corners.
Read more football betting tips and predictions.
Lille - 9/2
Draw - 16/5
Real Madrid - 4/7
View the full market and more odds for Lille v Real Madrid on site.
Read Lille v Real Madrid how to watch, TV channel, head-to-head stats, team news and more.
This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.
To bet on the UEFA Champions League, check out our betting hubs with everything you need to know including latest fixtures, odds, news, offers and guides.