Holders Real Madrid are off to a winning start in the 2024/25 UEFA Champions League and will be hoping to make it two out of two in France against Lille.
Kylian Mbappe set new club Real on the way to a 3-1 win over Stuttgart two weeks ago, on the same night as Lille were kicking off their group stage campaign with a 2-0 defeat at Sporting Lisbon.
Lille v Real Madrid is available to watch live in the UK on TNT Sports 5.
Lille v Real Madrid will kick-off at 20:00 BST on Wednesday 2nd October and is being played at Stade Pierre Mauroy in Villeneuve d'Ascq, France.
Lille, fourth in Ligue 1 last season, edged past Fenerbahce and Slavia Prague, both by 3-2 aggregate scores, to book their place in the UEFA Champions League league phase.
Their 2-0 loss in their league phase opener at Sporting was a fourth successive defeat in all competitions, though they won for the first time in six at the weekend, 3-0 at Le Havre with Jonathan David bagging a hat-trick.
Real, 15-time UEFA Champions League winners and reigning champions, are unbeaten in 10matches this season, winning seven. They last lost a competitive game in September 2023.
This is the first time these two clubs have met.
Lille coach Bruno Genesio is still missing long-term casualties Hakon Haraldsson, Ngal'ayel Mukau and Ismaily.
Kylian Mbappe's 17-year-old brother Ethan is also injured and England midfielder Angel Gomes is suspended after his sending-off at Sporting.
Kylian Mbappe missed Sunday's 1-1 draw at Atletico Madrid with a muscle strain, but is in the squad. Dani Ceballos, David Alaba and Brahim Diaz are still sidelined.
Goalkeeper Thibaut Courtois picked up a hip injury in the Madrid derby and will be replaced by Andriy Lunin.
Check out the bet365 betting hub for all the latest UEFA Champions League betting odds.