Italian giants Juventus begin their league phase campaign with a visit from Dutch champions PSV Eindhoven at teatime on Tuesday.
Juventus v PSV Eindhoven will be available to watch in the UK on TNT Sports 2 and Discovery+.
Juventus v PSV Eindhoven will kick off at 17:45 BST on Tuesday 17th September and takes place at the Juventus Stadium in Turin.
Surprisingly these two teams have never met before, despite both being previous winners of the UEFA Champions League - Juve in 1985 and 1996 and PSV in 1988.
The Italian aces began life under new head coach Thiago Motta with back-to-back 3-0 victories over Como and Verona in Serie A, before being held to goalless draws by both Roma and Empoli.
Motta said the stalemate at Empoli was "not what we wanted", but his side are yet to concede a goal this season.
PSV have begun the defence of their Eredivisie title in perfect style, winning five out of five to lead the way once more in the Netherlands, scoring 20 goals in the process and conceding just three.
Summer signings Teun Koopmeiners, Nico Gonzalez, Douglas Luiz and Pierre Kalulu all made their first Juve starts against Empoli, leaving Motta with plenty to ponder for the clash with PSV.
Francisco Conceicao and Arkadiusz Milik are both injured and will miss out.
PSV head coach Peter Bosz praised defenders Matteo Dams and Richy Ledezma for their performances in the 2-0 Saturday win over NEC Nijmegen, as his side kept a second consecutive clean sheet.
However, Hirving Lozano, who has scored four goals in four games this season, missed out due to a leg muscle injury and is unlikely to recover in time to face Juve.
To be on the UEFA Champions League,