Reigning World Cup champions Argentina sit comfortably atop the South America qualification table and they can maintain their lead at the summit with victory over Colombia.
Lionel Scaloni’s side have won six and lost one of their seven qualifiers so far this campaign and are currently on a 12-match unbeaten run across all competitions.
Colombia sit third in the table, five points behind leaders Argentina, and have not won any of their last four meetings with the White and Sky Blue, so a difficult day at the office could be in store.
The match will not be available to watch on TV in the UK but will be accessible through bet365's Sports Live Streaming service.
Colombia v Argentina will take place at the Estadio Metropolitano Roberto Melendez in Barranquilla on Tuesday 10th September with kick-off due for 21:30 BST
Argentina possess the much stronger head-to-head record with 21 wins from their 40 total meetings, with Colombia coming out on top on nine occasions.
The most recent meeting between the two sides came in the Copa America final back in July, with an extra-time winner from Inter Milan’s Lautaro Martinez sealing a record 16th title for La Albiceleste.
Colombia wins | 9 |
Draws | 10 |
Argentina wins | 21 |
* H2H stats refer to all competitions.
Two of Colombia’s most experienced players will miss this encounter through injury in goalkeeper David Ospina and defender Davinson Sanchez, however captain James Rodriguez could be in line to start.
The likes of Exequiel Palacios, Nicolas Tagliafico and Leonardo Balerdi are all unavailable through injury, however Alexis Mac Allister, Julian Alvarez and Paulo Dybala - who all scored in the 3-0 win over Chile last time out - should all feature.