There looks set to be no quarter given at Stamford Bridge on Saturday when Women's Super League champions Manchester City head to London to take on Chelsea, who claimed the title in each of the previous six seasons.
Both teams are unbeaten in this season's WSL, with the Citizens holding a two-point advantage at the top of the table after nine games of the 26-match campaign.
City head into battle having beaten Inter Milan 4-1 in the UEFA Women's Champions League on Tuesday, while Sonia Bompastor's hosts will want to show more up front after their goalless draw with Swedish outfit Hacken.
Chelsea Women v Manchester City Women Tips Summary
Best Bet - Draw or Manchester City Women - Double Chance @ 11/10
Alternative Bet - Khadija Shaw to score at any time @ 8/5
Bet Builder - Both teams to score, Melvine Malard 3+ shots & Kerstin Casparij to be booked @ 35/4
Chelsea Women v Manchester City Women Prediction
Best Bet: Draw or Manchester City Women - Double Chance @ 11/10
City got their hands on the Women's Super League trophy last season for the first time since 2016, ending Chelsea's six-year reign as champions, but, while the Londoners would love to get one over on their conquerors, it may not be as easy as that.
A draw with Manchester United has been the only time City have dropped a point in the league this season and, while Chelsea are also unbeaten. it seems the visitors head to Stamford Bridge in stronger form.
City beat Inter 4-1 in the UEFA Women's Champions League in midweek despite resting goal machine Khadija Shaw, who had scored a hat-trick the week before in a 5-0 win over West Ham.
Chelsea, meanwhile, have had to settle for home draws against Everton and Hacken in their last two outings and may not get the better of City this weekend.
Alternative Bet: Khadija Shaw to score at any time @ 8/5
City striker Khadija Shaw has topped the goalscoring charts in the WSL in each of the last four seasons and heads into Saturday's game with 12 goals to her name this term.
She comes fresh from a hat-trick in last week's 5-0 win over West Ham and the fact that she was rested for the midweek Women's Champions League action should be taken as an ominous sign.
The Jamaican forward can usually be relied upon on the biggest stage and has scored in each of her last seven appearances for the Citizens, so expect her to make her mark again at Stamford Bridge.
Chelsea Women v Manchester City Women Bet Builder Tip
Both teams to score
Melvine Malard 3+ shots
Kerstin Casparij to be booked
Pays 35/4
Both the goals Chelsea have conceded in home league games this season have been scored by their own players, but City possess one of the strongest strike forces in the WSL.
As champions, they will not be on a damage-limitation exercise like some of the Blues' other visitors and there looks a strong chance there will be goals at both ends as the best two teams in the league go at it.
Chelsea striker Melvine Malard has not scored in a home game since the 3-0 success over Birmingham City on 19th September, but she has not been shy in attempting to put that record right.
The French forward has had at least three efforts on goal in six of her last nine appearances for the Londoners and, while this represents a tough test for Bompastor’s side, it is worth chancing that she can match that statistic against the Citizens.
Meanwhile, the Citizens' Netherlands full-back Kerstin Casparij could be vulnerable to receiving a yellow card, having been booked in last week's victory over West Ham, in which she committed four fouls.
That was the third occasion in a club shirt that she was pulled up at least three times by the officials and she could be cautioned again in the most high profile game of the season so far.
Learn more about how Bet Builders work in our Bet Builder guide.
Key Match Stats
Manchester City Women have won just two of their last ten matches against Chelsea
Three of Chelsea Women's last four matches have featured fewer than three goals
Khadija Shaw has scored in her last seven appearances for Manchester City
Both teams have scored in 11 of Manchester City 13 matches this season
Chelsea have conceded four goals in their last 12 outings
Aston Villa and Everton are the only visiting teams to have scored against Chelsea this season and both were own goals
Read more football betting tips and predictions on site.
This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.
