Brentford will be aiming to make it two wins from their first three Premier League games of the season when they host newly-promoted Southampton.
The Bees lost 2-0 at Liverpool last weekend after winning their season opener 2-1 against Crystal Palace.
They will hope to pick up another three points when they face Saints, who have begun life back in the top flight with successive 1-0 defeats to Newcastle United and Nottingham Forest.
Both sides were victorious in midweek in the Carabao Cup, Brentford seeing off Colchester United 1-0, while Saints enjoyed a 5-3 win over Cardiff City.
Brentford to win and both teams to score - 12/5
After edging out Palace on the opening weekend, Brentford unsurprisingly fell to defeat at Liverpool last time out as Thomas Frank's side were beaten 2-0 at Anfield.
However, they had their moments against the Reds, with skipper Christian Norgaard and Nathan Collins both missing good chances and they were always a threat on the break and stayed competitive in the game until Mohamed Salah scored with 20 minutes to go.
A much-changed side then narrowly beat Colchester in the cup thanks to Keane Lewis-Potter's goal and Frank's men should approach the home clash with Saints with plenty of confidence.
Saints have yet to score upon their return to the Premier League, suffering 1-0 defeats at Newcastle and at home to Forest, but they should break their duck this weekend.
However, getting anything out of the trip Gtech Community Stadium may still prove to be beyond them.
Russell Martin's side were guilty of wasting plenty of opportunities against the Magpies on the opening weekend as they racked up 19 shots without getting on the scoresheet.
Then, while they were disappointing against Forest, the midweek cup victory at Cardiff should have lifted morale.
Martin made wholesale changes on Wednesday, but Cameron Archer did his chances of earning a league start the world of good with two goals against the Bluebirds.
Saints should at least be competitive against the Bees, even if they may have to wait longer for their first league win of the campaign.
Yoane Wissa to score anytime - 5/2
Wissa has already opened his account for the new season, scoring the winner against the Eagles, while he was lively against Liverpool as the Bees attempted to use his pace and trickery on the counter-attack.
The DR Congo international has been one of Brentford's main goal threats in the past three seasons and, after he registered seven league goals in both 2021-22 and 2022-23, he improved that figure up to 12 last term and he will be looking to at least get into double figures once again in this campaign.
Saints may only have conceded two goals so far, but they allowed Forest plenty of opportunities last week.
Nuno Espirito Santo's men had 23 shots in total at St Mary's and Brentford should also be capable of creating plenty of openings against them, with Wissa tipped to take advantage of any poor defending.
Flynn Downes to be booked - 15/8
Flynn Downes has started both games for Saints following his summer move from West Ham and he has been in the thick of the action in midfield.
The 25-year-old has already been booked, picking up a yellow card in the first half against Forest, and he may be in trouble with the referee this weekend too, as he attempts to help his side try and control the tempo of the game.
Downes seems a likely candidate for a booking against the Bees as he has given away six fouls across the two league games so far, more than any other Southampton player.
Read more football betting tips and predictions
Brentford - 8/11
Draw - 3/1
Southampton - 7/2
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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.