After an impressive first season under the leadership of Keith Andrews, Brentford have built on that this term and currently sit inside the top four.
In contrast, Liverpool are five places below their opponents and are going in search of just their third Premier League win of the campaign.
With several injuries impacting Andoni Iraola's squad, the Reds will need to rely on their more solid-looking backline if they are to get anything from their trip to the Brentford Community Stadium.
Best Bet - Under 2.5 goals @ 11/8
Alternative Bet - Over 4.5 cards @ 1/1
Bet Builder - Igor Thiago 2+ shots on target, Alexis Mac Allister 2+ fouls committed & Virgil van Dijk 1+ headed shots on target @ 18/1
Best Bet: Under 2.5 goals @ 11/8
Liverpool could be without six first-team squad members for the trip to west London, with Iraola likely to make several changes to the team that won in Austria on Wednesday.
The Reds racked up a 6-3 UEFA Champions League victory over LASK, but were still missing Alexander Isak, Cody Gakpo and Dominik Szoboszlai.
The trio remain doubtful for Saturday's league clash, while the Merseysiders will also be missing Ryan Gravenberch through suspension following his red card against Manchester City.
When you consider the 2024-25 champions are already missing Hugo Ekitike and Conor Bradley, it highlights the selection problems for the manager.
One thing Iraola has done to good effect is shored up the Reds at the back, with Liverpool keeping clean sheets in three league games prior to the Citizens defeat.
Brentford's defensive record is also impressive, with the Bees leaking just six goals in their first six league matches - conceding just one in their three home games.
It's also worth noting that three of the last four meetings between the sides have seen under 2.5 goals, including a 1-1 draw at Anfield last season.
Alternative Bet: Over 4.5 cards @ 1/1
Both of these teams are inside the Premier League top five for yellow cards this term, with Brentford collecting 16 cautions and Liverpool 14.
Nobody has more cards than Bees midfielder Vitaly Janelt, with the German picking up four yellows in the opening six league fixtures.
Recent encounters between these two teams have delivered a busy 90 minutes for the man in the middle - who is John Brooks on Saturday afternoon.
There have been five cautions in each of the last four matches between Brentford and Liverpool, while referee Brooks has dished out 19 yellows in his four top-flight games this season.
Igor Tiago 2+ shots on target
Alexis Mac Allister 2+ fouls committed
Virgil van Dijk 1+ headed shots on target
Pays 18/1
Only five players have registered more Premier League shots than Igor Thiago this season, with the Brazilian racking up 13 attempts.
The 25-year-old scored 22 goals last season but only has one so far this term, so Tiago - who scored a penalty in this fixture last October - will be desperate to add another.
With the suspended Gravenberch missing out, Alexis Mac Allister will have a big role to play in midfield for the visitors.
The Argentinian has started four league games for the Reds this season and has committed eight fouls to date.
Question marks over the fitness of Isak and Gakpo will again leave Liverpool's striking options limited, a concern when it comes to finding the net.
One of their best chances to break down a stubborn Brentford backline will be from set-pieces and Virgil van Dijk - who was rested in midweek - will be their main target from corners.
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Last season's 3-2 success in this fixture was Brentford's only win in their last seven meetings with Liverpool
Brentford rank third in the Premier League for Expected Goals (10.96), with Liverpool currently ninth (9.28)
Liverpool are unbeaten in their four away games in all competitions, claiming three wins and one draw
The Bees have had nine different scorers in the Premier League this season
Only Milos Kerkez remains a Liverpool player from the last seven goalscorers for the Reds against Brentford
Eight of the last 12 goals in this fixture have been scored in the second half
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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.
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