The latest instalment of El Clasico will take place in the Copa del Rey as rivals Barcelona and Real Madrid meet at the Estadio Olimpico de Sevilla on Saturday night.
The two teams have already met on two occasions this season, with Barcelona winning 4-0 in La Liga in October before recording a 5-2 victory in the Spanish Super Cup in January.
Barcelona are leading the way in the race for the league title and they hold a four-point advantage over Real Madrid, with the two teams set to meet in La Liga for a second time on 11th May.
Barcelona to win - 23/20
Hansi Flick's team will fancy their chances of winning the club's 32nd Copa del Rey trophy and Barcelona still have the chance to win four trophies this season.
With the Spanish Super Cup already glistening in the trophy cabinet, Barcelona have the advantage in La Liga, while they remain in the UEFA Champions League.
Flick's team will face Inter Milan in the semi-finals of the competition, while crucially, reigning champions Real Madrid were eliminated by Arsenal in the quarter-finals.
Both teams come into the game on the back of successive victories in the league, with Barcelona beating Celta Vigo 4-3 and Mallorca 1-0, while Real Madrid recorded two 1-0 wins over Athletic Bilbao and Getafe.
Barcelona will be without striker Robert Lewandowski due to a hamstring injury, but they can call upon the services of Ferran Torres. The former Manchester City man is not a bad replacement in the final third, with Torres scoring 17 times this season, despite not being guaranteed a starting jersey.
Flick's team have not lost a domestic game since December, and the manner of their previous victories over Real Madrid this season suggest they will once again outclass them this weekend.
Over 2.5 goals - 1/2
So much is made of games between Barcelona and Real Madrid and it is usually for good reason. Two of the best teams in Europe often put everything on the line in order to get the better of each other, and while the fixtures are usually fiery contests, they are also highly entertaining.
There have been at least three goals scored in seven consecutive meetings, while 14 of the last 15 meetings have contained at least three goals.
Despite only scoring one goal in each of their last six games, Real Madrid have the squad capable of performing on the big stage, and they have already conceded nine goals to Barcelona this season, so expect another end-to-end classic.
Raphinha anytime goalscorer - 8/5
Lewandowski's injury is a bitter blow for Barcelona, with the La Liga top scorer set to return in May in time for the next El Clasico battle.
The Poland international has scored 40 goals in all competitions for Blaugrana, but Flick has managed to get the best out of Torres and Raphinha.
Former Leeds United ace Raphinha is in contention to win the Ballon d'Or this season after netting 30 goals and 23 assists in all competitions.
The Brazil international has already scored three times against Real Madrid this season and he continues to perform on the big stage for his club.
With Lewandowski sidelined, Raphinha will look to lead by example and take the game to Real Madrid. He has registered a shot on target in six of his last seven appearances, while he has had 23 shots in seven appearances.
Raphinha is at the heart of everything Barcelona do in attack, and he should make another big impression this weekend.
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Barcelona - 23/20
Draw - 29/10
Real Madrid - 21/10
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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.