We take a look at all of the standout results and hot talking points from the weekend across the biggest leagues on the continent - La Liga, Serie A, Bundesliga and Ligue 1...
There were plenty of eye-catching results to take in from across Europe, none more so than at Civitas Metropolitano where the local bragging rights went the way of Atletico Madrid, who ended Real Madrid's 100% start to the new campaign.
In France, there was a return to form on the domestic front for Paris Saint-Germain, who put four past managerless Marseille in the first Le Classique of the season, while it was seventh heaven for Harry Kane's Bayern Munich in the Bundesliga.
Real went into Sunday's Madrid Derby a perfect five wins from five in La Liga this season, but Carlo Ancelotti's side were brought back down to earth with a bang against their fierce rivals Atletico, losing 3-1.
To add insult to injury for Los Blancos, it was one of their former players, Alvaro Morata, who proved the difference maker for Atleti, as he grabbed a brace to help his side to only their second league win over Real in their last 15 attempts.
It was an uncharacteristically subdued performance from Real, with even Jude Bellingham, who had previously scored six goals in six appearances following his summer move from Borussia Dortmund, being kept quiet.
The win has lifted Atleti up to fifth and they are 11/1 to be crowned champions this season, while Real remain favourites for the title despite slipping to third with this loss.
Barcelona (6/5) have taken Real's place at the top of the standings after they sensationally recovered from two goals down after 81 minutes of their home clash with Celta Vigo to win 3-2 - Robert Lewandowski grabbing a brace for Xavi's side.
Barca are joined on 16 points by this season's surprise package Girona, who won an eight-goal thriller with Mallorca 5-3 to extend their unbeaten start to the campaign.
La Liga Results:
Only two teams across Europe's top five leagues still have 100% records in their domestic divisions, Manchester City are one and the other is Inter Milan, who made it six victories from six in Serie A with a hard-fought 1-0 success at Empoli.
This result and performance did not have the same razzmatazz as the previous week's thrashing of AC Milan in the derby, but Federico Dimarco's fantastic second-half volley was enough to seal the points for Simone Inzaghi's side, who are to end the season as champions.
AC Milan are up to second after bouncing back from their derby disappointment with a 1-0 success over Hellas Verona at the San Siro - Rafael Leao's early strike proved the difference in that one.
The Rossoneri are 7/2 second favourites for the title after Juventus (5/1) and defending champions Napoli () both dropped points - the Old Lady going down 4-2 at Sassuolo, while the Partenopei were left frustrated by a goalless draw at Bologna.
Those results leave Juve fourth and Napoli seventh, both below an unfancied Lecce, who are up to third following Friday's 1-0 win over Genoa.
Roberto D'Aversa's side are one of two teams, alongside Inter, yet to taste defeat in Serie A this season.
Serie A Results:
For the second time in the space of just a few days, Bayern Munich were involved in a seven-goal thriller, but after getting the better of Manchester United 4-3 in the Champions League during the week, Saturday's 7-0 thrashing of Bochum was far more straightforward.
Harry Kane was one of the stars of the show for Thomas Tuchel's side, grabbing his first hat-trick since joining from Tottenham in the summer, while he also provided two assists.
England captain Kane is now on seven Bundesliga goals for the season, but he is not leading the scoring charts in Germany, with Stuttgart's Serhou Guirassy moving into double figures after his brace in his side's 3-1 victory over Darmstadt.
Saturday's win was also enough to move Bayern top of the standings on goal difference, ahead of Bayer Leverkusen, who also enjoyed a big win, beating Heidenheim 4-1 on Sunday.
Other contenders, RB Leipzig (10/1) and Borussia Dortmund (14/1), also enjoyed victories this weekend, the former winning 1-0 at Borussia Monchengladbach, while the latter edged out Wolfsburg by the same scoreline on home turf.
Paris Saint-Germain had made an underwhelming start to the new domestic season in France, winning just two of their opening five matches in Ligue 1.
However, they appeared to kick-start their campaign on Sunday night, thrashing Marseille 4-0 in Le Classique, but that victory came at a cost, as Kylian Mbappe was forced off during the first half with an apparent ankle issue.
Head coach Luis Enrique moved to play down fears surrounding the injury after the match, describing it as a "knock", but with a huge Champions League trip to Newcastle United to come in just over a week's time, there will be concerns surrounding the France superstar.
The win for PSG has moved them up to third, behind surprise leaders Brest, who maintained their impressive start as they spoiled Fabio Grosso's debut in the Lyon dugout, claiming a 1-0 victory at the Stade Francis-Le Ble thanks to a goal from former Huddersfield Town forward Steve Mounie.
Monaco had come into the weekend topping the standings, but they were beaten 1-0 on home turf by Nice on Friday night - that result has lifted the visitors up to second and, alongside Rennes, they are the only unbeaten teams left in Ligue 1.
Ligue 1 Results: