A second evening of FA Cup fifth-round action comes along on Wednesday and Manchester United are part of our acca as the Red Devils continue their quest for a domestic cup double.

Erik ten Hag's side had few problems against an underwhelming Newcastle United at Wembley on Sunday and it's unlikely that Premier League strugglers West Ham will prevent the Red Devils taking a step closer to being back in the capital for the FA Cup decider.

Elsewhere, Championship high-flyers Burnley should come through against Fleetwood Town, while Southampton and Grimsby Town may scrap it out in a low-scoring affair on the south coast, with our treble selection giving out odds of 20/1.

And all the FA Cup action on Wednesday evening is available on bet365's Sports Live Streaming.

FA Cup Fifth Round Wednesday three-fold acca:

Our FA Cup treble is priced at 20/1:

Man United to win to nil @ 7/4

Southampton vs. Grimsby Under 2.5 goals @ 11/8

Burnley to win & both teams to score @ 9/4

Odds correct at time of publishing and subject to change

United can hold Hammers off unscathed

What	Manchester United v West Ham
Where	Old Trafford, Manchester
When	19:45, Wednesday 1st March
How to watch	bet365 Sports Live Streaming and ITV
Odds	Man Utd 8/13, Draw 3/1, West Ham 9/2

West Ham's continuing status as a Premier League club must surely be the priority for David Moyes ahead of the Scot's return to Old Trafford.

Three away games in eight days include this and a Europa Conference League trip to AEK Larnaca next Thursday, with Brighton sandwiched in between at the weekend.

That trip to the Seagulls must surely take priority, with the Hammers still precariously positioned despite the 4-0 London Stadium win over Nottingham Forest that lifted them out of the relegation zone last time out.

West Ham have failed to score in five of their last nine away games in the Premier League and they might well find United tough to break down here, especially with Danny Ings - who got the first two goals against Forest on Saturday - ineligible for the cup tie.

The last six meetings between these sides at Old Trafford have yielded under 2.5 goals and so a low-scoring home win looks the best way to go, with United having run out 1-0 winners in four of the last six meetings between the sides.

Five of the last six meetings between these sides have resulted in just one of the teams scoring, so 7/4 for the hosts to win to nil makes plenty of sense.

Ten Hag's revolution in Manchester went up a notch with that Wembley win on Sunday and United have lost just one of the last 20 against the Irons at home.

With United on a high after hoisting silverware, they are expected to win this, but it might not be all guns blazing if they did manage to enjoy themselves following their Wembley success.

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Cagey affair likely at St Mary's

What	Southampton v Grimsby Town
Where	St Mary's, Southampton
When	19:15, Wednesday 1st March
How to watch	bet365 Sports Live Streaming and ITV4
Odds	Southampton 3/10, Draw 17/4, Grimsby 17/2

League Two Grimsby Town are the visitors to Premier League basement boys Southampton with an FA Cup quarter-final spot on the line.

Rather like West Ham, the Saints have a major relegation battle on their hands after they were beaten 1-0 at Leeds United in a six-pointer on Saturday, leaving them remaining bottom of the Premier League with four points between them and safety.

New permanent manager Ruben Selles has his work cut out and, while West Ham's eye may be turned to other targets, a home defeat against opponents three tiers below really wouldn't do much for morale in the Saints camp, so they'll be eager to get a win.

They were semi-finalists in the Carabao Cup last month and should book a last-eight FA Cup berth now, as their Full Time Result odds of 3/10 to win suggest. 

Grimsby are 16th in League Two, but are unbeaten in their last three league matches and they upset Luton Town in the previous round. 

Southampton are the Premier League's third lowest scorers with 19 in 24 games, while Grimsby have one of the better defensive records of the teams around them in League Two. 

The visitors will be aiming to contain for long spells, surely, and with Southampton not exactly high in confidence right now, they might have to settle for a low-scoring win, ensuring under 2.5 goals looks sound value in the Goals Over/Under market for this one at 11/8.

Fleetwood to keep Kompany's Clarets honest

What	Burnley v Fleetwood Town
Where	Turf Moor, Burnley
When	19:30, Wednesday 1st March
How to watch	bet365 Sports Live Streaming and BBC Red Button
Odds	Burnley 1/4, Draw 9/2, Fleetwood Town 12/1

Vincent Kompany is well on his way to becoming a Premier League manager with his Burnley side cruising towards promotion from the Championship.

The Clarets have built their success on a rock-solid record at Turf Moor, where they've yet to lose this season and have won 13 of 18 games in the Championship, scoring 40 times.

They put four past Huddersfield Town at the weekend in a comprehensive win, after the 'blip' of two draws in three before that.

In fact, Burnley's only defeat in 15 games came against Manchester United back in December in the Carabao Cup, one of only three defeats so far this season suffered by the former Manchester City skipper Kompany as boss. 

Fleetwood have their own high-profile boss, with ex-Celtic captain Scott Brown cutting his teeth in the dugout after hanging up his boots last season.

They took a scalp of sorts in the previous round, knocking out League One leaders Sheffield Wednesday 1-0 as the Owls failed to follow-up their own giant-killing effort - having handed Newcastle a rare defeat at Hillsborough in round three. 

That win for Fleetwood is part of a good run that has yielded five wins and a draw of late. and they are in mid-table in England's third tier, although the playoffs are surely out of reach now. It has, though, been a decent first season for Brown as boss. 

Burnley are by some way the leading scorers in the Championship, average two goals per game, but they were pushed hard by Ipswich in the last round, winning 2-1 via Nathan Tella's goal in stoppage time after both teams has scored inside four minutes at the start.

With league stalemates since against Watford and Millwall, it's now just three clean sheets in six for Burnley. 

Fleetwood's season will begin to meander aimlessly if they exit the FA Cup, so they will be eyeing a big performance and they should get on the scoresheet.

The hosts, however, should have too many firepower and a Burnley win with both teams to score at 9/4 completes our Wednesday evening FA Cup accumulator.