England will take on Uruguay and Japan in friendlies ahead of next summer's World Cup.
The South American side will be the first to visit Wembley on 27 March, with a clash against Japan coming four days later.
The fixtures will mark England's final games at the Home of Football before they head to North America in search of a first World Cup win since claiming the trophy on home soil more than half a century ago.
Thomas Tuchel's side will enter the tournament in the United States, Mexico and Canada as one of the favourites to go all the way after breezing through qualification without conceding a single goal.
On Friday, England learned their group stage fate at the 2026 World Cup final draw from Washington DC. The Three Lions have been placed in Group L alongside Croatia, Ghana and Panama.
Uruguay have been a common rival for England, and the home side will be keen to banish the memories of the last time the two teams met.
At the 2014 World Cup in Brazil, a Lewis Suarez-inspired Uruguay side defeated England, with the result ultimately condemning the Three Lions to their first group stage exit at FIFA's showpiece since 1982.
The two-time World Cup winners were also the only team to avoid defeat against Sir Alf Ramsey's vaunted side that would go on the claim the trophy in 1966, holding the hosts to a goalless draw in the opening game of the tournament.
England will have happier memories of playing Japan however, having never lost against the AFC giants.
The last time the two teams met came back in May 2010 during the lead up to the World Cup in South Africa. England ran out 2-1 winners despite none of their players getting on the scoresheet.
Own goals from Marcus Tanaka and Yuji Nakazawa saw Fabio Capello's side come back from a goal down to claim victory at the Liebenauer Stadium in Graz, Austria.
