Reigning European champions Italy take on Zlatko Dalic's Croatia in a decisive contest in Leipzig with both teams seeking to book their place in the Euros knockout rounds.
Luciano Spalletti's Italy sit second in Group B on three points following a 2-1 victory over Albania in their opening match, whilst Croatia lie bottom of the pile with just one point from their first two outings - picked up in a 2-2 draw against the Albanians.
This means the need for victory in Leipzig is particularly crucial for Luka Modric and Co. as Croatia bid to progress through to the knockout rounds in a major tournament for the fifth time in a row.
Italy are priced as 7/5 favourites to prevail in this vital encounter, whilst Croatia are underdogs at 21/10.
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Two-time winners of the Euros, Italy looked assured in their opening game against a plucky Albania side, but appeared rather toothless in attack in their second match when faced with an impressive Spain outfit.
Croatia have also looked somewhat short of attacking thrust in their opening two matches - with Hoffenheim striker Andrej Kramaric their only player to have found the net in Germany thus far - and this encounter with Italy in Leipzig could prove a tight affair.
The Italians are priced at 3/1 to win and Both Teams not to Score, whilst Croatia are given odds of 9/2 to prevail and keep a clean sheet.
If Italy are to make a breakthrough, Federico Chiesa could well be the inspiration, with the Juventus winger starring in the Azzurri's opening game triumph against Albania following which he received UEFA's Player of the Match award.
Scoring 10 goals in all competitions for Juventus last season, Chiesa is priced at 7/1 to be the First Goalscorer as Italy take on Croatia.
As for Croatia, ex-Leicester City striker Kramaric is given odds of 7/1 to strike first in Leipzig after notching last time out against Albania.
(Odds will display when markets are available)
All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.