Atlético de Madrid welcome Manchester United to the Estadio Metropolitano in an eagerly anticipated UEFA Champions League clash on Tuesday night.
Atleti took the lead in their European opener against Premier League giants Liverpool in September, but goals from Dominik Szoboszlai and Alexis Mac Allister saw them fall to a 2-1 defeat.
The Spanish outfit are enjoying a fruitful run of form in La Liga however, defeating Alaves at the weekend to extend their unbeaten run to four games.
It's been a familiar story so far this season for Man Utd, who are without a win in four after drawing 1-1 against Tottenham Hotspur last time out.
They did come out on top in their only UEFA Champions League game this term however -- defeating Sabah 4-0 in Matchweek 1 -- and they'll be looking to end their dismal away form in the competition in the Spanish capital.
Diego Simeone has made four changes to the Atleti side that overcame Alaves in narrow 2-1 fashion on Saturday.
David Hancko returns in place of Robin Le Normand at the heart of defence.
A midfield change sees Pablo Barrios replace Koke, while Jonathan David and Ademola Lookman make way for Lee Kang-in and Julian Alvarez in attack.
Carrick has made five alterations to the Man Utd XI that could only manage a point against Tottenham last time out.
Diogo Dalot and Ayden Heaven return to the defence in place of Harry Maguire and Luke Shaw.
Amad Diallo drops out of the team for Andrey Santos. Carlos Baleba will make his full Red Devils debut, replacing Kobbie Mainoo. This is likely to see Youri Tielemans deployed in the number 10 position, while Bruno Fernandes could shift to the right flank.
Meanwhile, Marcus Rashford is back in the side in place of Matheus Cunha.
Atlético de Madrid starting XI
Jan Oblak, Marcos Llorente, Cristian Romero, David Hancko, Alejandro Grimaldo, Johnny Cardoso, Giuliano Simeone, Pablo Barrios, Alex Baena, Lee Kang-in, Julian Alvarez.
Manchester United starting XI
Senne Lammens, Diogo Dalot, Leny Yoro, Lisandro Martinez, Ayden Heaven, Andrey Santos, Carlos Baleba, Youri Tielemans, Marcus Rashford, Bruno Fernandes, Bryan Mbeumo.
