The Philadelphia Eagles face an important test of their mettle six days after losing their undefeated status in one of the most interesting matchups Week 12 has to offer.
Elsewhere, the Minnesota Vikings have a shot at taking over as the NFC's number one seeds if results go their way and the Kansas City Chiefs can end the Los Angeles Chargers' claims on the AFC West division title.
Eagles to bounce back
| What | Philadelphia Eagles @ Indianapolis Colts |
| Where | Lucas Oil Stadium, Indianapolis |
| When | 1 p.m. ET/10 a.m. PT Sunday, November 20th |
| How to watch | CBS, Streaming via Paramount + |
| Odds | PHI Eagles -310, IND Colts +250 |
The Eagles are coming off their first defeat of the season whereas the Colts enjoyed a surprise victory under their new interim coach to reignite their playoff hopes last week - so can they maintain their momentum?
Indianapolis is probably not an ideal place for the Eagles to go looking for an easy win right now. This should be a much closer game than the oddsmakers expect after giving Philadelphia the edge by a touchdown.
The Colts got their running game going again after the return of Jonathan Taylor, the league's leading rusher from 2021, in Las Vegas last week.
He put up almost 150 yards on the ground and broke out for a 66-yard TD run in the third quarter, but Indy still needed Matt Ryan to ice the game with a well-balanced touchdown drive in the final quarter.
In their 32-21 defeat to the Washington Commanders last Monday, the Eagles looked vulnerable to a team fully committed to staying with the run and dominating the time of possession, which worked twofold as it wore down Philly's interior defensive lineman and kept Jalen Hurts off the field.
A similar gameplan and execution would put the outcome at Lucas Oil Stadium in the lap of the gods, so it may be best to take Indy with the +7.0 point Spread here at -120.
Cowboys ready to strike
| What | Dallas Cowboys @ Minnesota Vikings |
| Where | U.S. Bank Stadium, Minneapolis, Minnesota |
| When | 4.25 p.m. ET/1.25 pm PT Sunday, November 20th |
| How to watch | CBS, Streaming via Paramount + |
| Odds | DAL Cowboys -125, MIN Vikings +105 |
The Cowboys dropped to 6-3 with their overtime defeat in Green Bay last weekend, which has subsequently been made to look even worse by the Packers' Thursday night loss to the Tennessee Titans.
Dallas are uneasy favourites for this road game against a surging Vikings team that downed the Buffalo Bills last week to win another close battle.
Justin Jefferson had a major influence on the outcome in Buffalo and shutting him down will be the key here for a Cowboys' secondary that had some blown coverages exploited by Aaron Rodgers last Sunday.
Facing their second road game in a row against a tougher opponent than last should put most people off the Cowboys in this spot, but there's something telling about the oddsmakers' confidence in Mike McCarthy's men.
The Cowboys held Jefferson to two catches for 21 yards in last year's matchup - a 20-16 win in Minneapolis - and could be worthy of support straight up at -125.
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Chargers can hurt Kansas
| What | Kansas City Chiefs @ Los Angeles Chargers |
| Where | SoFi Stadium, Inglewood, California |
| When | 8.20 p.m. ET/5.20 pm PT Sunday, November 20th |
| How to watch | NBC, Streaming via fuboTV |
| Odds | KC Chiefs -235, LA Chargers +195 |
A road success for the Chiefs should put them three wins up on their biggest division rivals with seven weeks to go. But, if the Chargers can cause an upset, the AFC West title race is open again.
Chargers wide receivers Keenan Allen and Mike Williams, who had an outstanding game in LA's 27-24 loss at Arrowhead in week 2, have not played a complete game together all season, but could both be fit to face the Chiefs for this prime-time clash.
The Bolts were beaten by the San Francisco 49ers in Week 10, but match up better to the Chiefs.
They can take Patrick Mahones' comfort blanket - tight end Travis Kelce - away from him with the sort of coverage that smothered George Kittle last week.
The Chiefs QB has been on fire of late and it would not be wise to doubt his playmaking ability even if Kelce cannot get open, but the value here is in opposing Kansas City by taking Los Angeles with a +5.0 point Spread at -110.
The Chiefs, who are 4-5 against the spread in 2022, have not won by more than three points in regulation in any of the last five head-to-head meetings, although they did engineer two overtime wins by a TD in that run.
